In a mixing bowl, combine ground turkey, breadcrumbs, Parmesan cheese, minced garlic, onion powder, salt, black pepper, oregano, Worcestershire sauce, and the egg. Mix until just combined.
Divide the mixture into 4 equal portions and shape each portion into a patty, about 3/4 inch thick. Make a small indentation in the center of each patty to prevent puffing while cooking.
Preheat your grill or skillet over medium-high heat. Lightly grease the grill or skillet with cooking oil spray or brush.
Once hot, add the turkey patties to the grill or skillet. Cook for about 5 minutes on one side until golden brown, then flip and cook for an additional 5 minutes, or until the internal temperature reaches 165°F (74°C).
While the burgers are cooking, toast the whole wheat buns on the grill or in a toaster.
Assemble the turkey burgers by placing a patty on each bun. Top with lettuce, tomato slices, pickles, and your choice of condiments.
Serve immediately and enjoy!